Atlanta Center for Medical Research

Interested in volunteering for a clinical study? Please fill out the following form so that we may determine your eligibility for one of ACMR’s ongoing or upcoming studies.

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Hepatic impairment occurs when your liver fails to process due to damage from previous viruses, harmful chemicals, and overconsuming substances like alcohol. This is a serious condition that can lead to the shut down of your liver, which will lead to coma and then death.

There are two major types of hepatic failure. The first is acute liver failure, which is a fast-moving disease that causes your liver to loss function within days or weeks. It usually occurs after consuming something poisonous. The second type of hepatic failure is chronic liver failure. It develops when scar tissue begins to form over regular liver tissue, causing the liver to eventually fail. This process happens much slower and can take years to notice its effects.

Here are the symptoms associated with hepatic impairment:

  • Nausea
  • Weight loss
  • Loss of appetite
  • Fluid buildup in the abdomen
  • Fluid buildup in the legs
  • Itching
  • Diarrhea
  • Fatigue
  • Bruising or bleeding more easily
  • Jaundice

Treatment for this condition can be difficult. Sometimes medications work, but other times your doctor will recommend removing parts of the liver. Since so many of the symptoms described above can be confused with other conditions and medical issues, diagnosing hepatic impairment can often happen too late, meaning a liver transplant will be required to undo the damage already done.

Participating in a study will allow medical professionals to continue to study and identify early symptoms of hepatic impairment to help recognize it earlier, continue to improve treatment options, and will help us understand the disease better.


The Atlanta Center for Medical Research was founded in 1982 by Dr. Robert A. Riesenberg and is now one of the largest and most respected medical research institutions in the country. ACMR’s 150,000-square-foot, state-of-the-art, open-source research facility is a game changer for the medical research world. ACMR’s practices set the standard for medical research, facilitating the availability of safe and effective medicine to people everywhere.

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